Just to say, while it's easier to use Blender if you know the hotkeys, you don't have to. I began in 2.4x just using menus for everything but extruding, translating, and rotating. It's even easier now. Hotkeys are convenient, but most of what you'll want to do will be in the 3D window under Object in Object mode and Select and Mesh in Edit mode.
I've never had a problem making clothes in Blender. I've been able to model pretty much any clothing I want within a few hours, unless I'm spending time exploring techniques or topologies. That's why I have so very, very many unfinished projects (and almost all will probably remain unfinished). Admittedly, I tend to put details in my textures (including displacement and bump maps), because I like my clothes to be very versatile, and I found early on that if I modeled in detail, I had to fight to make what I wanted to make when I got to texturing. For instance, I'll probably never model a catsuit with sections and such, because then I couldn't change those sections around when I wanted to, and I can do just fine with maps. That said, I'm also good with jewelry, so it's not as if I have a problem with modeling details.
Point being, if you ask me questions about how to do something in Blender in terms of modeling clothes, there's at least a decent chance I can answer.
It's converting them into something that works for me, texturing them, etc. that's what takes my time and effort. If I could figure out how to make some fancy buttons work on Dawn's back, I'd have already made one dress I probably will finish into a product. I've tried rigging (which I suck at), I've tried dynamic-constrained, and I've tried dynamic - hard decorated. Everything distorts too much. I'm sure there's a way to do it, but I haven't found it so far. If anyone has advice, just let me know.
For those who like Zbrush, you might check out Blender's sculpting tools. They're nowhere near as smooth as Zbrush, but they're improving steadily. Not only is the Blender community holding Zbrush as the standard, but I'm seeing more and more crossover in the community galleries. As far as I can tell, Blender/Zbrush is becoming a pretty common pairing.