AFAIK, not in a straight way. All solutions that I saw used either temp matfile/posefile (Netherworks) or nodetree recreation (Snarlygribbly, BB). Or, as a variation of the former, template matfile, where the script reads it, insert/change image files references, and saves with another name. (Made such script for myself, helps a lot with flowers packages, when you have a lot of texture options.) Had an intention to look at pickle way to do it, but still didn't. Had enough of Zope world before switched to Django.